Vitamin K2 in arterial stiffness and vascular calcification

Vitamin K2 is essential for blood health,1 vascular health,2 and normal coagulation.1 There is increasing evidence that micro-calcification plays a role in atherosclerosis and is an active player in plaque progression and destabilisation. Vitamin K2 has shown beneficial effects in arterial stiffness,2,3 vascular calcification, and micro-calcification.2 A 3-year double-blind, placebo-controlled trial in healthy postmenopausal women found that 180 micrograms/day of Vitamin K2 (MenaQ7) decreased arterial stiffness compared to placebo.3

1Sato T, et al. Nutrients. 2020 Mar 31;12(4):965.

2Florea A., et al. Eur J Prev Cardiol, 2020 Mar 2,

3Knapen M.H., et al. Thromb Haemost. 2015;113(5):1135-44.