Potential of Gymnema in Metabolic Syndrome

Gymnema (Gymnema sylvestre) is a herb I regularly use for patients with metabolic syndrome, glucose intolerance, and insulin resistance. I first learned about Gymnema in my first year of studying Naturopathy in 1996. I generally combine Gymnema with Cinnamon, Chromium, Garcinia, Magnesium, Milk Thistle, Vitamin B6, and Zinc. I find this combination very helpful in people with glucose intolerance, insulin resistance, and metabolic syndrome. The Magnesium, Vitamin B6, and Zinc can be taken as separate supplements or found in combination. Milk Thistle improves liver health, which can be an issue with some people with metabolic syndrome.

Some of the benefits of Gymnema include increasing the secretion of insulin and utilisation of glucose, cholesterol lowering properties, anti-inflammatory, hepatoprotective, and modulation of taste, particularly suppressing sweet taste sensations.

I found an article from 1926 which stated that Gymnema leaves reduced the taste sensation of sugar.

Getting excited. A couple of days until I start my PhD at the University of Sydney. Woohoo.


Gharpurey KG. Gymnema Sylvestre in the Treatment of Diabetes. Ind Med Gaz. 1926 Mar; 61(3): 155.

Kanetkar P et al. Gymnema sylvestre: A Memoir. J Clin Biochem Nutr. 2007 Sep; 41(2): 77-81.

Porchezhian E, Dobriyal RM. An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents. Pharmazie. 2003 Jan; 58(1): 5-12.